Mouse fibroblasts are isolated from Irf3^-/-xlrf5^-/-xlrf7^-/-TKO mice. Researchers generated the mouse strains from an inbred C57BL/6 background.

Associated Publication: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling