Summaries by Inventor Unanue, Emil

Peptides responsible for Type 1 diabetes
Lichti, Cheryl ; Unanue, Emil ; Wan, Xiaoxiao
T-018626

— Technology Description: Researchers in the lab of Emil Unanue at Washington University have discovered a panel of peptides responsible for autoimmune activation in Type 1 diabetes and potentially capable of diagnosing T1D at an early stage. These peptide fragments of insulin are found circulating …

B-122 and Alf-161 – Hamster IgG Monoclonal Antibodies against Mouse/Rat IL-1 Beta and Mouse IL-1 Alpha
Chaplin, David ; Schreiber, Robert ; Unanue, Emil
T-000125

— Target: Mouse/rat interleukin-1 beta and mouse interleukin-1 alpha. Located on macrophages, dendritic cells, T and B cells. Notes: Clone name is B-122 and Alf-161Information on antibodies against IL-1 beta: The role of murine IL-1 beta in vitro and in vivo has not been defined. We describe here the production of neutralizing and immunoprecipitating mAb and polyclonal antibodies specific for murine IL-1 beta and their application to a characterization of the…

Knockout Mouse lacking Expression of the Batf3 Gene
Diamond, Michael ; Murphy, Kenneth ; Murphy, Theresa ; Schreiber, Robert ; Unanue, Emil
T-009136

— Notes: Batf3-/- knockout mouse with a 129SvEv background.