Summaries by Inventor Thackray, Larissa

LDLRAD3 KO mice
Diamond, Michael ; Thackray, Larissa
T-019372

— Venezuelan equine encephalitis virus (VEEV) is an emerging infectious disease in South America transmitted by mosquitos. VEEV usually resides in forest and swamp areas where human populations are limited, however, VEEV has the potential to cause epidemics in humans and equines. LDLRAD3 has been foun…

Novel Murine Astroviruses
Loh, Joy ; Stappenbeck, Thaddeus ; Thackray, Larissa ; Virgin, Herbert ; Wang, David ; Yokoyama, Christine ; Zhao, Guoyan
T-012077

— Background: Mice are critical animal models for scientists investigating both basic and applied research principles. Several novel murine astroviruses have been identified in mouse facility at Washington University School of Medicine. Astroviruses are RNA viruses often associated with gastrointestin…

Target and Method to Treat Alphavirus Infections
Basore, Katherine ; Diamond, Michael ; Fremont, Daved ; Kim, Arthur ; Nelson, Christopher ; Thackray, Larissa ; Zhang, Rong
T-017583

— Published date: 1/14/2026 Value Proposition: Fusion protein that can be used to prevent and treat arthritogenic alphavirus infections. Technology Description Researchers at Washington University in St. Louis have identified MXRA8 (matrix remodeling associated protein 8) protein as a key recepto…

Fusion protein for treating multiple strains of Venezuelan equine encephalitis virus
Basore, Katherine ; Diamond, Michael ; Fremont, Daved ; Kafai, Natasha ; Kim, Arthur ; Ma, Hongming ; Thackray, Larissa
T-019414

— Published date: 1/14/2026 Value Proposition: Decoy receptor therapeutic that can treat multiple VEEV subtypes by blocking VEEV entry and infection. Technology Description Researchers at Washington University in St. Louis have developed a decoy Ldlrad3-D1-Fc protein for prevention of treatment o…