Summaries by Inventor Sheehan, Kathleen

Hamster Monoclonal IgG2a Antibody against Mouse IFN-Beta
Schreiber, Robert ; Sheehan, Kathleen

— Description: HDbeta-4A7- mouse IgG2a monoclonal antibody reactive with murine Interferon-beta. This mAb has neutralizing activity. Publication:

Hamster Monoclonal IgG Antibody against Mouse IFN-Alpha
Schreiber, Robert ; Sheehan, Kathleen

— Description: TIF-3C5- Armenian hamster monoclonal antibody reactive with murine Type I Interferons, including IFN alpha A, 1, 4, 5, 11 and 13 but not IFNbeta. This mAb can block functional activity. Publication:

Hamster Hybridoma producing Monoclonal Antibody against Mouse CXCL9
Schreiber, Robert ; Sheehan, Kathleen

— Target: Inflammatory chemokine CXCL9, monokine induced by IFN-gamma. Secreted mainly by macrophages. Notes: Clone MIG-2F5-5. Use in ELISA, neutralizing and binding assays.

Hamster Hybridoma producing Monoclonal Antibody against Murine IFNAR-1
Schreiber, Robert ; Sheehan, Kathleen

— Target: Type-1 interferon receptor subunit, a key signaling receptor in the interferon pathway. Notes: Clones MAR1-5A3, MAR1 -1H5, MAR1-3A7, MAR1-4D12, MAR1-4F12Monclonal antibodies specific for MuIFNAR1 were isolated from hybridomas developed following immunization of IFNAR1 gene targeted mice with purified plasmid encoding the the extracellular domain of murine IFNAR1 expressed in pRK5 using a method of hydrodynamic immunization. Publication:


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