Summaries by Inventor Pirzada, Mujeeb
Antisense Oligonucleotides (ASOs) to Treat Neurodegeneration in ALS and FTD
Djuranovic, Sergej ; Pirzada, Mujeeb
T-021032
Djuranovic, Sergej ; Pirzada, Mujeeb
T-021032
— Published Date: 5/14/2025 Value proposition: Novel ASOs that increase key protein production to limit neurodegeneration caused by ALS and frontotemporal dementia (FTD). Technology Description TDP-43 pathology is present in ~97% of ALS, ~50% of FTD, and frequently observed in other neurodegenerat…