Summaries by Inventor Naegle, Kristen
Kinase toolkit for the production of phosphorylated proteins
Gale, Emily ; Naegle, Kristen ; Schaberg, Katherine ; Sloutsky, Roman ; Stoka, Kellie
T-014736
Naegle, Kristen ; Silva, Jonathan ; Zhu, Wandi
T-018631
Gale, Emily ; Naegle, Kristen ; Schaberg, Katherine ; Sloutsky, Roman ; Stoka, Kellie
T-014736
— Background: Abnormal phosphorylation of proteins is associated with a number of human diseases including cancer, neurodegenerative disorders, and diabetes. Due to their role as phosphorlyators, kinases are popular drug targets. However, the difficulty of selectively phosphorylating a desired substra…
New Method for Predicting a Patient’s Response to Drug Therapy for Treatment of Irregular Heart RhythmsNaegle, Kristen ; Silva, Jonathan ; Zhu, Wandi
T-018631
— Value Proposition: New process that uses ion channel voltage sensing parameters to predict antiarrhythmic drug response. Technology Description Researchers at Washington University in St. Louis have developed a new process for predicting patients’ response to mexiletine drug therapy. Mexil…
