Summaries by Inventor Miller, Timothy
Therapeutic targeting of LDL in ALS
Kreple, Collin ; Miller, Timothy ; Nielsen, Susan ; Racette, Brad
T-020021
Dougherty, Joseph ; Hoye, Mariah ; Hyman, Theodore ; Koval, Erica ; Miller, Timothy
T-015167
Kreple, Collin ; Miller, Timothy ; Nielsen, Susan ; Racette, Brad
T-020021
— Technology Description Researchers in Brad Racette and Tim Miller’s labs at Washington University have developed a therapeutic strategy for treating ALS by using statins to lower LDL. Statins were successful at prolonging both survival and time with a normal gait. The researchers identif…
microRNA biomarker and drug target for ALS and other motor neuron diseasesDougherty, Joseph ; Hoye, Mariah ; Hyman, Theodore ; Koval, Erica ; Miller, Timothy
T-015167
— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…
