Summaries by Inventor Fehniger, Todd

Ncr1-ERT2iCre Mice
Fehniger, Todd
T-018981

— This mouse strain is a novel Natural Killer cell specific inducible cre that is useful for studying the development, maturation, and function of NK cells. It has a tamoxifen inducible Ncr1-ERT2iCre mouse allele that is used for floxing gene(s) of interest out of NK cells. This model was designed, cr…

Cytokines-induced-memory-like NK cells with reduced NKG2A checkpoint signaling
Berrien-Elliott, Melissa ; Fehniger, Todd ; Romee, Rizwan
T-017001

— Background: Natural Killer (NK) and T cells are the primary immune cells being explored for cancer immuntherapy. NK cells are relatively short-lived, making the therapy less susceptible to some of the side effects currently associated with using T cells for immunotherapy. Unlike T cells, NK cells ar…