Summaries by Inventor Dougherty, Joseph
Mice with Mutant Gtf2i and Gtf2ird1 Alleles
Dougherty, Joseph ; Kopp, Nathan
T-019290
Dougherty, Joseph
T-018757
Dougherty, Joseph ; Hoye, Mariah ; Hyman, Theodore ; Koval, Erica ; Miller, Timothy
T-015167
Dougherty, Joseph ; Kopp, Nathan
T-019290
— Dr. Dougherty developed a collection of mouse lines with deletions of Gft2i and Gtfird1 in various combinations. The genes are related to Williams Beuren locus. Publications:
Egr1Cre;Snap25Flp mice (On deposit with Jackson Labs – Strain 033895)Dougherty, Joseph
T-018757
— Egr1Cre;Snap25Flp mice
microRNA biomarker and drug target for ALS and other motor neuron diseasesDougherty, Joseph ; Hoye, Mariah ; Hyman, Theodore ; Koval, Erica ; Miller, Timothy
T-015167
— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…
