Summaries by Inventor Djuranovic, Sergej

Simple, universal DNA motifs for modulating protein production
Djuranovic, Sergej

— Technology Description Researchers in Prof. Sergej Djuranovic’s laboratory have discovered short DNA coding motifs that can increase or decrease expression of recombinant proteins by 3-4 orders of magnitude in a variety of organisms. Together, these universal tools can provide tightly contro…

An alternative approach in antimalarial drug design
Djuranovic, Sergej ; Erath, Jessey Lee ; Pavlovic Djuranovic, Slavica

— Technology Description Researchers in Sergei Djuranovic’s lab at Washington University have developed polybasic peptides and polymers to block Plasmodium falciparum adhesion as a treatment for malaria. These therapeutics reduce parasite infection of human cells, making this a promising alter…

Plasmid library for miRNA, Pumilio, Smaug and AU-rich elements
Djuranovic, Sergej

— This is the pcDNA-5 plasmid library with 6500 barcoded constructs containing eGFP followed by 650 combinations of 3’UTRs with miRNA, Pumilio, Smaug and AU-rich. This library can be used to optimize gene expression and to study gene regulation by different micro RNAs and RNA-binding proteins. …


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