Summaries by Inventor Cruchaga, Carlos
Cruchaga, Carlos
T-021415
— Published date: 9/18/2025 Value Proposition: Process that can be used to quantify the amount of DNA contamination in an RNA isolation tube. Technology Description Researchers at Washington University in St. Louis have developed a method to determine the amount of DNA contamination in an RNA extr…
Highly Accurate Model used to Predict Alzheimer’s Disease StatusAli, Muhammad ; Cruchaga, Carlos
T-020673
— Technology Description Researchers at Washington University in St. Louis have developed models that can very accurately predict brain amyloidosis—Alzheimer’s disease status. Alzheimer’s disease (AD) is characterized by the accumulation of Amyloid-β (Aβ42) and hyperphos…
Blood-based biomarkers of Alzheimer’s disease for diagnostics and clinical trialsCruchaga, Carlos ; Dube, Umber ; Ibanez, Laura
T-019198
— Technology Description: Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …
Improved Alzheimer’s Disease Detection Using Cell-Free RNA AnalysisCisterna Garcia, Alejandro ; Cruchaga, Carlos ; Ibanez, Laura
T-020079
— Published Date: 5/10/2025 Value Proposition: Method that uses plasma cfRNAs to differentiate Alzheimer’s disease from healthy controls. Technology Description Researchers at Washington University in St. Louis have developed a series of models using blood-based biomarkers to detect Alzheimer…