Summaries by Inventor Burgess, Robert
Floxed ChAT mouse strain
Burgess, Robert ; Sanes, Joshua
T-019107
Burgess, Robert ; Sanes, Joshua
T-019107
— This mouse strain has loxP sites flanking exons 3 and 4 of the ChAT gene. There is a Neo gene in the intron between exons 4 and 5. Mating these mice to A-Cre mice generates a null allele in subsequent generations, in which no ChAT protein or activity is detectable. The mice are maintained in the C57…