Psychiatry Summaries

Subtyping of schizophrenia based on genome and pathology
Cloninger, C. Robert ; Svrakic, Dragan ; Zwir, Jorge "Igor"

— Technology Description Researchers in Igor Zwir’s lab at Washington University have developed a diagnostic system to categorize patients with schizophrenia into 8 sub-groups. The system recommends a sub-group based on both genetic and psychopathology data and provides clinicians with a knowl…

Compound to treat alcohol use disorder
Covey, Douglas ; Mennerick, Steven

— Technology Description Researchers at Washington University in St. Louis have developed new compounds that may be used to treat alcohol use disorder (AUD). AUD, a common condition that takes a high personal and public health toll, is characterized by severe problems with drinking- sufferers may co…

Therapeutic Approach for Huntington’s Disease (HD)
Kim, Albert ; Yano, Hiroko

— Dr. Hiroko Yano and Dr. Albert Kim, and their research teams at the Washington University School of Medicine in St. Louis developed and extensively evaluated a novel therapeutic approach using DNMT inhibitors to treat Huntington’s Disease (HD) and other neurodegenerative disorders. Currently D…

Neurofibromin/dopamine signaling as a biomarker for cognitive and behavioral problems in children with neurofibromatosis type 1 (NF1)
Anastasaki, Corina ; Gutmann, David

— Background: Neurofibromatosis type 1 (NF1) is a common neurological condition affecting roughly 1 in every 2,500 individuals. NF1 is associated with a host of clinical presentations, including malignant tumors and cognitive defects ranging from attention deficits, mental retardation, and autism. The…

VISIT-TS Version 2
Black, Kevin ; Gordon, Mollie ; Schroeder, Miriam ; Striley, Catherine ; Vachon, Matthew

— This is a brief (5 minutes exposition plus just under 5 minutes of questions) video that was designed for epidemiological research in tic disorders (including Tourette syndrome). The video shows lay people the broad definition of tics, so they can more accurately answer questions about whether they…

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