Nephrology-Renal Summaries
Chen, Ying ; Kim, Yeawon
T-016375
— Technology Description Researchers in Prof. Ying “Maggie” Chen’s laboratory have identified three sensitive, urine-based biomarkers of kidney disease that could be used for non-invasive, early detection and clinical trials monitoring. In particular, these mechanistic biomarkers a…
Kidney disease biomarkers for diagnosis, prognosis or clinical trials monitoringChen, Ying ; Kim, Yeawon
T-016375
— Technology Description Researchers in Prof. Ying “Maggie” Chen’s laboratory have identified three sensitive, urine-based biomarkers of kidney disease that could be used for non-invasive, early detection and clinical trials monitoring. In particular, these mechanistic biomarkers a…
Anti-MIOX antibodies for sensitive, specific early detection of acute kidney injuryCrimmins, Dan ; Gaut, Joseph ; Ladenson, Jack ; Laterza, Omar ; Lockwood, Christina ; Modur, Vijay
T-013292
— Technology Description A team of researchers at Washington University in St. Louis have developed patented antibodies designed to identify MIOX (myo-inositol oxygenase), a renal-specific biomarker that can be detected immediately following acute kidney injury (AKI). AKI can be caused by surgery, s…
Arteriovenous graft designed to prevent thrombosis and graft failureGenin, Guy ; Williams, Dillon ; Zayed, Mohamed
T-018994
— Technology Description Prof. Mohamed Zayed and colleagues have developed an arteriovenous graft cuff with features designed to normalize the blood shear rate and decrease risk of thrombosis at the venous end anastomosis. This device could reduce the failure rate of these grafts, thereby improving …
miRNA mimics to treat metabolic diseaseGong, Yong-feng ; Hou, Jianghui
T-017930
— Disease indication: metabolic disorders including insulin resistance and diabetic nephropathy Drug format: chemically modified synthetic microRNA (miRNA) Drug class: first-in-class for metabolic disease Research stage and Preliminary data: Target: miR-29 mimics can increase the gene expressio…
PET tracer to diagnose kidney diseaseBaldelomar, Edwin ; Beeman, Scott ; Bennett, Kevin ; Reichert, David
T-018902
— Technology Description Researchers at Washington University in St. Louis have developed a PET tracer that may be used to quantify kidney nephron endowment and diagnose kidney disease. Nephrons are the functional units of the kidney responsible for filtering the blood to remove waste. They are form…
PET tracer to diagnose kidney diseaseBaldelomar, Edwin ; Beeman, Scott ; Bennett, Kevin ; Reichert, David
T-018902
— Technology Description Researchers at Washington University in St. Louis have developed a PET tracer that may be used to quantify kidney nephron endowment and diagnose kidney disease. Nephrons are the functional units of the kidney responsible for filtering the blood to remove waste. They are form…
MRI and PET nanoparticle imaging agents for kidney disease diagnostics and transplant evaluationBaldelomar, Edwin ; Bennett, Kevin
T-019017
— Technology Description: Researchers at Washington University in St. Louis have developed targeted, natural nanoparticle imaging agents that may be used to quantify kidney nephron endowment and diagnose renal disease with MRI or PET imaging. Nephrons are the functional units of the kidney responsi…
