Musculoskeletal Disorders, Orthopedics-Bone Summaries
Johnson, Tim ; Leuthardt, Eric ; Moran, Daniel ; Reynolds, Benton ; Stoev, Ivan ; Wright, Neill
T-016236
— Technology Description A team of researchers at Washington University have developed ACALADE (Advanced Capability Lumbar Discectomy), a device designed to help surgeons safely access and quickly remove the back portions of herniated discs for faster, lower risk lumbar discectomy. Currently, about…
Wearable Finger Goniometer for Hand PhysiotherapyPet, Mitchell
T-021195
— Published date: 9/12/2025 Value Proposition: Wireless device that offers a range of motion biofeedback to patients undergoing hand therapy. Technology Description Researchers at Washington University in St. Louis have developed a device designed to provide continuous, real-time kinematic biofee…
Adhesive coated sutures for stronger musculoskeletal repairsGenin, Guy ; Linderman, Stephen ; Thomopoulos, Stavros
T-014989
— Technology Description An interdisciplinary team at Washington University in St. Louis has developed patented adhesive-coated sutures with the potential to reduce ruptures following surgical repair of tendons and ligaments. These modified sutures are designed to minimize stress by shifting the mec…
Biomimetic device for stronger repair of rotator cuff and other soft tissue-to-bone tearsGalatz, Leesa ; Genin, Guy ; Hoppe, Ethan ; Smith, Lester ; Thomopoulos, Stavros ; Yoon, Dong Hwan
T-019211
— Technology Description A team of engineers led by Professor Guy Genin has developed a device to strengthen the reattachment of soft tissue to bone for use in orthopedic procedures such as rotator cuff repairs. Although tendon and ligament tears are common, the techniques used to reattach these tis…
Gene-Specific Therapy Treatment for Predicting Limb-Girdle Muscular DystrophyHaller, Gabriel ; Li, Chengcheng ; Weihl, Conrad
T-020804
— Published Date: 5/14/2025 Value Proposition: Method that uses gene-therapy to detect limb-girdle muscular dystrophy (LGMD) type 4R/2E. Technology Description Researchers at Washington University in St. Louis have developed a method of predicting limb-girdle muscular dystrophy (LGMD) type 4R/2…
Osteogenic Screw System for Stimulating Bone GrowthLeuthardt, Eric ; Moran, Daniel
T-005419
— Published date: 1/9/2025 Value Proposition: Osteogenic device that provides a focal current through a bone construct to induce bone formation and fusion in patients. Technology Description Researchers at Washington University in St. Louis have developed an osteogenic screw system that can perfo…
Engineered Polymer-Peptide for Treatment of Lower Back Pain Caused by Chronic Back PainBarcellona, Marcos ; Setton, Lori ; Speer, Julie
T-019297
— Value Proposition: Tissue engineering scaffold for cell differentiation and delivery to intervertebral disc for treating back pain. Technology Description Researchers at Washington University in St. Louis have developed an engineered peptide-functionalized polymer that can support healthy nucle…
Epigenetic drug targets to treat or prevent osteoarthritis and cartilage degradationMcAlinden, Audrey ; O'Keefe, Regis ; Shen, Jie
T-015627
— A team of researchers at Washington University in St. Louis has identified an epigenetic pathway and two therapeutic targets that could be used to prevent cartilage loss and counteract the mechanism underlying osteoarthritis. The inventors have seen promising results in a mouse model of arthritis us…
Early, specific, blood-based diagnostic for septic arthritisLuhmann, Scott
T-018905
— Technology Description: Researchers at Washington University in St. Louis have identified blood-based cytokine signatures that could be used to specifically detect, distinguish and monitor septic arthritis, synovitis and osteomyelitis. This assay could enable timely, accurate treatment to avoid joi…
Exosome-based therapy for tendon injuries and other soft tissue repairShen, Hua
T-018565
— Technology Description: A team of researchers at Washington University has developed a cell-free, nano-sized extracellular vesicle (EV/exosome) system to enhance repair of soft musculoskeletal tissue. This technology leverages the natural anti-inflammatory effects of adipose-derived stem cells (ASC…
Software to predict low back pain from brain imagingHawasli, Ammar ; Jayasekera, Dinal ; Lamichhane, Bidhan ; Leuthardt, Eric ; Ray, Wilson
T-019322
— Technology Description: Researchers at Washington University, led by Eric Leuthardt, have developed software that can identify specific brain regions involved in chronic low back pain from neuroimaging data. This software, powered by machine learning, relies on differences in cortical thickness an…
Computer-Implemented Method for Measuring StrainsBoyle, John ; Genin, Guy ; Pless, Robert ; Thomopoulos, Stavros
T-014090
— Published date: 1/7/2025 Value Proposition: Accurate, efficient 2D strain mapping with robust detection of strain localization. Technology Description Researchers at Washington University in St. Louis have developed a novel method using 2D Direct Deformation Estimation (2D-DDE) and SIMPLE (St…
