Dermatology-Hair Summaries

Therapeutic targets for atopic dermatitis
Kim, Brian ; Wang, Fang

— Researchers at Washington University’s Center for the Study of Itch & Sensory Disorders have discovered a novel histamine-independent pathway that could be targeted to treat atopic dermatitis. Atopic dermatitis (AD) is a chronic inflammatory skin disease that presents with itch as its mos…

An Intradermal Method for the Treatment of Hair Loss and Alopecia
Feng, Jing ; Hu, Hongzhen ; Luo, Jialie ; Yang, Pu

— Technology Description: A team of researchers, led by Hongzhen Hu, at Washington University in St. Louis has developed a method of treating hair loss and alopecia by intradermal injection targeting TRPV4 activation. Using a small molecule TRPV4 agonist, a single intradermal injection is sufficient…

Targeting CD5+ Dendritic Cell in Skin for the Treatment of Chronic Diseases
Klechevsky, Eynav

— Background Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…

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