Nanomaterials Summaries

Nanothermometers for cellular-level temperature monitoring in ablation therapy or research
Berezin, Mikhail ; Gustafson, Tiffany
T-012606

— Technology Description Researchers in Prof. Mikhail Berezin’s laboratory have developed patented, fast-acting, gold nanoparticle-based optical “nanothermometers” that can detect temperature changes at the cellular level by emitting a fluorescent signal. These molecules were desig…

Flame Aerosol Reactor (FLAR) Based Process for Fabricating Nanostructured Films for Solar Energy Applications with Unique Compositions
Biswas, Pratim ; McDonald, Rafael ; Thimsen, Elijah
T-006824

— The invention is a new process for fabricating nano-structured metal-oxide and other films. The films can harvest solar energy in the form of light and convert it to a more usable form (i.e: electricity or hydrogen gas). The films produced by this process have a unique morphology that grants them a …

Development of Colloidal Iron Oxide Contrast Agent for MRI and MPI
Lanza, Gregory ; Pan, Dipanjan ; Senpan, Angana ; Wickline, Samuel
T-007545

— Background: Biodegradable magnetic carriers have been increasingly utilized in biomedical and clinical research, but the larger size of ferromagnetic agents previously used leads to long circulation times and restriction to the vasculature, making these particles ideally suited for detection of spa…

Tuning of photo-absorption in semiconductors, photoconductors, and other photo conversion systems using magnetic fields
Hayes, Sophia ; Mui, Stacy ; Ramaswamy, Kannan
T-008875

— Background: The idea of creating clean, sustainable power in high amounts from renewable energy sources is an interest among many across the globe. One of the many ways of creating renewable energy is applying the photovoltaic effect, the conversion of solar to electrical energy, by using semiconduc…

Single nanoparticle detection and sizing by mode-splitting in an ultra-high-Q microresonator
Chen, Da-Ren ; He, Lina ; Ozdemir, Sahin ; Yang, Lan ; Zhu, Jiangang
T-009642

— With the rapid progress in nanotechnology, a variety of nanoparticles of different materials and sizes have been synthesized and engineered as key components in various applications ranging from solar cell technologies to biomolecular detection1-3. Meanwhile, nanoparticles generated continuously by …

Disulfide trapped antigenic peptide in an MHC molecule.
Connolly, Janet ; Fremont, Daved ; Hansen, Ted ; Lybarger, Lonnie ; Miley, Michael ; Mitaksov, Vesselin ; Truscott, Steven
T-004551 Water filtration platform technologies using crumpled graphene oxide nanocomposites
Biswas, Pratim ; Fortner, John ; Jiang, Yi ; Wang, WeiNing
T-014428

— Technology Description A team of researchers at Washington University, led by Pratim Biswas and John Fortner, has constructed crumpled graphene oxide nanoparticles encapsulating TiO2 and Ag to create reactive, easily cleaned water filtration membranes. The TiO2 and Ag, which can be periodically re…

Encapsulation to protect detection antibodies in implantable and wearable biosensors
Chakrabartty, Shantanu ; Gupta, Rohit ; Luan, Jingyi ; Morrissey, Jeremiah ; Scheller, Erica ; Singamaneni, Srikanth
T-019364

— Technology Description An interdisciplinary team of researchers at Washington University have developed a universal system designed to extend the lifetime of implantable and wearable biosensors by protecting detection antibodies from harsh conditions and enabling a refreshing process to release bo…

SPECT imaging nanoprobe for the detection of matrix metalloproteinase (MMP) activity
Achilefu, Samuel ; Black, Kvar
T-014635

— This invention is the formulation of a SPECT nanoparticle probe for the detection of MMP activity. The surface of a 10 nm-sized gold nanoparticle is functionalized through a thiol anchor with a peptide that is cleaved in the presence of MMP9. The surface is also functionalized with methoxy polyethyl…

Low-cost, environmentally friendly synthesis of delta-MnO2 nanosheets for battery cathodes, catalysts and remediation
Jun, Young-Shin ; Jung, Haesung
T-018510

— Technology Description Engineers in Prof. Young-Shin Jun’s laboratory have developed a cost-effective, fast, green chemistry process to produce birnessite (δ-MnO2) nanosheets with naturally abundant resources. This method uses sunlight and nitrate to oxidize Mn2+ (aq) to Mn (IV) and ha…

Artificial antibody platform to eliminate cold-chain in label-free plasmonic biosensor detection for diagnostics and research
Abbas, Abdennour ; Kharasch, Evan ; Liu, Keng-Ku ; Morrissey, Jeremiah ; Singamaneni, Srikanth ; Tian, Limei
T-013772

— Technology Description An interdisciplinary team of researchers at Washington University have developed a patented plasmonic nanotransducer system with built-in, highly stable artificial antibodies that can quickly detect and quantify biological molecules. These artificial antibodies can be rapidl…

Low-cost, high-performance materials for solar-driven membrane distillation in water treatment and desalination
Jiang, Qisheng ; Jun, Young-Shin ; Singamaneni, Srikanth ; Wu, Xuanhao
T-019047

— Technology Description Engineers in Prof. Young-Shin Jun’s laboratory and Prof. Singamaneni’s laboratory have developed high performance, stable membrane materials that can be used for photothermal membrane distillation (PMD) to purify or desalinate water with minimal input of electric…

Low-cost, environmentally friendly synthesis of delta-MnO2 nanosheets for battery cathodes, catalysts and remediation
Jun, Young-Shin ; Jung, Haesung
T-018510

— Technology Description Engineers in Prof. Young-Shin Jun’s laboratory have developed a cost-effective, fast, green chemistry process to produce birnessite (δ-MnO2) nanosheets with naturally abundant resources. This method uses sunlight and nitrate to oxidize Mn2+ (aq) to Mn (IV) and ha…

Imaging and treatment of pathophysiologic conditions by Cerenkov Radiation
Achilefu, Samuel ; Kotagiri, Nalinikanth
T-013974

— Background: Around 1 million patients receive radiation therapy every year with an estimated cost of $2,000 per treatment. The market demands technologies that can provide efficacious therapeutics and diagnostic imaging while minimizing harmful side effects. Photodynamic therapy can simultaneously s…

Nanocomposite fertilizer for efficient phosphorus uptake and sustainable agriculture
Biswas, Pratim ; Raliya, Ramesh
T-016378

— Technology Description Engineers in Prof. Pratim Biswas’ laboratory have developed a nanoparticle fertilizer that increases phosphorus uptake and plant yield while reducing environmental damage and strain on natural resources. Increasing global food demand has prompted the large-scale use o…

Nanomaterial to eliminate cold chain by preserving biological reagents and patient samples
Kharasch, Evan ; Morrissey, Jeremiah ; Singamaneni, Srikanth ; Wang, Congzhou
T-017288

— Technology Description An interdisciplinary team at Washington University has developed low-cost, easy-to-use, nanoparticles that can preserve antibodies, proteins and other biological molecules without refrigeration. This technology employs metal organic frameworks (MOF) that can be used in two w…

Spray Pyrolysis for the Production of Li+ Ion Battery Cathodes
Atlas, Gal ; Axelbaum, Richard ; Elhassid, Dror ; Lengyel, Miklos
T-013647

— Background Material morphology and composition are critical for production of Li+ ion battery cathodes, and there is a need for improved synthesis methods that yield high quality materials through cost effective, green, scalable processes. Further, there is often a need to dope materials during syn…

Nanomaterial to eliminate cold chain by preserving biological reagents and patient samples
Kharasch, Evan ; Morrissey, Jeremiah ; Singamaneni, Srikanth ; Wang, Congzhou
T-017288

— Technology Description An interdisciplinary team at Washington University has developed low-cost, easy-to-use, nanoparticles that can preserve antibodies, proteins and other biological molecules without refrigeration. This technology employs metal organic frameworks (MOF) that can be used in two w…

Spray Pyrolysis for the Production of Li+ Ion Battery Cathodes
Atlas, Gal ; Axelbaum, Richard ; Elhassid, Dror ; Lengyel, Miklos
T-013647

— Background Material morphology and composition are critical for production of Li+ ion battery cathodes, and there is a need for improved synthesis methods that yield high quality materials through cost effective, green, scalable processes. Further, there is often a need to dope materials during syn…

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