by | Feb 25, 2022 | Li, Jr-Shin
— Technology Description
Engineers in Prof. Jr-Shin Li’s laboratory have developed a computationally efficient analytical technique to design exact RF pulse code sequences which optimize quantum applications such as MRI for medical diagnosis, NMR spectroscopy for uncovering protein structures …
by | Feb 23, 2022 | Cui, Jianmin
— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)
Drug format – Small molecule
Drug class – Lead compounds are repurposed drugs
Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…
by | Feb 18, 2022 | Elbert, Donald, Roam, Jacob
— Technology Description
Engineers led by Dr. Donald L. Elbert have developed a patented, self-assembling hydrogel microsphere scaffold system designed to improve tissue regeneration by creating cell migration pathways to repair large nerve gaps. This technology generates the migration pathways by c…
by | Jan 25, 2022 | Bowman, Gregory
— Technology Description
Researchers in Greg Bowman’s lab at Washington University have developed an improved method for rational drug and protein design called Boltzmann docking. This process better incorporates the dynamic structures of proteins to identify sites for binding that are not rev…
by | Jan 21, 2022 | Wang, Qing, Wang, Yong
— Technology Description
Researchers at Washington University in St. Louis have developed MRI post-processing software capable of imaging cellular components. The software matches specific patterns with a dictionary of signals corresponding to cellular components. While the researchers have previous…