by | Oct 22, 2019 | Tai, Yuan-Chuan
— Background
PET-CT scanners have been widely used in the identification of tumors and localization for biopsies due to its superior ability to detect biochemical and physiological functions. However, one of the main limitations of PET-CT is the inability to visualize soft tissues, which may be impor…
by | Oct 22, 2019 | Barnes, Jonathan, Delawder, Abigail "Abby", Li, Ruihan, Li, Xuesong
— Background
Targeted delivery of cytotoxic therapeutics is crucial to prevent adverse side effects of chemotherapy and to increase drug concentrations at the tumor site. These prerequisites also apply to the treatment of infections caused by multiple drug resistant bacteria. To address this unmet n…
by | Oct 22, 2019 | Bateman, Randall, Elbert, Donald
— Background
Quantitation of relative or absolute amounts of proteins by mass spectrometry can be prone to large errors. The use of MS/MS ion intensities and stable isotope labeling, a method called isotope labeling tandem mass spectrometry (SILT), decreases the effects of contamination from unrelate…
by | Oct 22, 2019 | Chen, Hong, Williamson, Jeffrey, Yang, Yaoheng "Mack"
— Technology Description
Researchers in Prof. Hong Chen’s laboratory have developed a safe, convenient monitoring technique to precisely deliver drugs to the brain by integrating ultrasound imaging with ultrasound therapy (focused ultrasound-blood-brain-barrier delivery, “FUS-BBBD”…
by | Oct 22, 2019 | Li, Lei, Wang, Lihong, Yao, Junjie
— The invention is a novel photoacoustic imaging technique, termed reversibly switchable photoacoustic tomography (RS-PAT). It exhibits a large penetration depth, a high detection sensitivity, and a spatial super-resolution. The most important feature of this technique is that it significantly incre…