scFv-TR3: TRAIL trimers targeted to mesothelin

— WUSTL Technology 016481

Technology Description

Researchers at Washington University in St. Louis have developed an additional targeting strategy to provide more flexibility and improve the bioactivity of the anticancer therapeutic TR3. This strategy targets TR3 to mesothelin, a tumor biomarker fr…

Machine learning method for fast, reliable quality assurance of patient imaging in radiation therapy or computer-aided detection

— Technology Description

A team of researchers at Washington University has created a machine learning method to quickly and reliably validate patient contours in digital medical images for radiation therapy and computer aided image analysis.

Currently, automated contouring tools for delineating tu…

Steerable Thermoablation Probe for Improved Access to Brain Lesions

— Technology Description

An interdisciplinary team led by Professor Eric Leuthardt has developed a steerable device that can be integrated into existing thermoablation systems to treat abnormal brain lesions. Thermoablation is a more targeted and less disruptive method for treating lesions than chem…

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