by | Mar 5, 2020 | Chung, Charles, Kovacs, Sandor, Shmuylovich, Leonid, Zhang, Weixiong
— Technology Description
Researchers in the Cardiovascular Biophysics Laboratory at Washington University developed a patented, real-time, automated index to reliably detect delayed relaxation during cardiac catheterization diagnostics. This technique, called pressure recovery ratio (PRR), serves as…
by | Jan 15, 2020 | Boyle, Walter
— Background: Vasodilatory shock, a reduction in effective blood circulation, occurs when endogenous vasoconstrictor mechanisms fail as a result of an often lethal combination of severe infections. Sepsis, as one of the causes, alone affects 1 million people resulting in more than 258,000 deaths each …
by | Oct 22, 2019 | Kharasch, Evan, Morrissey, Jeremiah, Singamaneni, Srikanth, Tadepalli, Sirimuvva
— Technology Description
An interdisciplinary team of researchers at Washington University have developed a sensitive, shelf-stable, label-free system for quickly quantifying biomarkers in point-of-care settings (e.g., office, ambulance or battlefield). Localized surface plasmon resonance (LSPR) off…
by | Oct 22, 2019 | Cupps, Brian, Pasque, Michael
— Background: Assessing left ventricle (LV) cardiac contractile function is a good indicator of overall heart health and is used to determine which patients are good candidates for revascularization surgery. With over 3 million new coronary artery disease patients annually and over 1 million annual re…
by | Oct 22, 2019 | Ladenson, Jack, Landt, Yvonne, Laterza, Omar
— This is a monoclonal antibody specific for NT-Pro BNP and can be used singly in a competitive immunoassay to measure the amount of this analyte in blood samples for the purpose of diagnosis or monitoring of congestive heart failure. In addition, it could be used in a sandwich immunoassay with a mono…