by | Jun 11, 2025 | Cashin, John, Roberts, Sophia, Rucker, Devaughn, Zayed, Mohamed
— Published Date: 6/12/2025
Value Proposition: Endovascular ventricular device that improves blood flow at lower rotational speed.
Technology Description
Researchers at Washington University in St. Louis have developed a toroidal endovascular ventricular support device (TEVAD) that is design…
by | May 14, 2025 | DiPersio, John, Ghobadi, Armin, O'Neal, Julie, Ritchey, Julie
— Published Date: 5/13/2025
Value Proposition: An innovative therapy leveraging unique chimeric antigen receptors (CAR) to specifically target Fc receptor-like 5 (FCRL5), enabling the precise elimination of FCRL5-expressing cells to treat multiple myeloma and other cancers.
Technology Description
…
by | Dec 13, 2024 | Silva-Fisher, Jessica
— Value Proposition: Long non-coding RNA as biomarker and therapeutic target for treating diagnosed multiple myeloma patients.
Technology Description
Researchers at Washington University in St. Louis have developed a long non-coding RNA as a diagnostic marker and clinical target for multiple my…
by | Feb 21, 2024 | Luff, Stephanie, Sturgeon, Christopher
— T-018886 — Scalable Generation of Hematopoietic Progenitors from Human Pluripotent Stem Cells
Technology Description
In vitro generation of CD34+ hematopoietic progenitor cells (HPC) that faithfully recapitulate in vivo behavior is an area of ongoing research. A key characteristic of CD34+ …
by | Mar 9, 2022 | Alhallak, Kinan, Azab, Abdel Kareem
— Disease indication – multiple myeloma
Drug format – antibodies conjugated to nanoparticles for T-cell immunotherapy
Drug class – improved delivery platform
Research stage and Preliminary data:
In vivo:
In vitro proof of concept – in a MM cell line: NanoMuTEs and NanoTC…