by | Jun 24, 2021 | Ances, Beau, Butt, Omar, DiPersio, John, Ghobadi, Armin
— Technology Description:
Researchers at Washington University in St. Louis have developed a biomarker screening assay to predict which patients receiving CAR T cell therapy will experience neurotoxicity. Patients can be screened well in advance of receiving the T cell therapy with a simple serum as…
by | Jun 11, 2021 | Shen, Hua
— Technology Description:
A team of researchers at Washington University has developed a cell-free, nano-sized extracellular vesicle (EV/exosome) system to enhance repair of soft musculoskeletal tissue. This technology leverages the natural anti-inflammatory effects of adipose-derived stem cells (ASC…
by | Jun 3, 2021 | Jun, Young-Shin, Zhu, Yaguang
— Technology Description
Researchers in Young-Shin Jun’s lab at Washington University have developed a more sustainable and efficient process for extracting rare earth elements from coal fly ash using supercritical fluids. Compared to the conventional roasting and acid leaching method, supercr…
by | May 19, 2021 | Colonna, Marco
— Disease indication – In combination with anti-PD-1 therapy for cancer. Anti-PD-1 therapy is currently approved for:
Drug format – Monoclonal antibody
Drug class – First-in-class
Target – TREM2
Research stage and preliminary data – The inventors performed initia…
by | May 19, 2021 | Hotchkiss, Richard, Mazer, Monty, Remy, Kenneth, Turnbull, Isaiah
— Technology Description
A team of researchers, led by Richard Hotchkiss at Washington University in St. Louis, have developed a version of the ELISpot assay to determine if COVID-19 patients are in a hyper-inflammatory or immunosuppressed state. The results of this assay, which can be performed wit…