by | Sep 3, 2020 | Hu, Yifei, Van Dyke-Blodgett, Joshua
— Background:
Compounds containing piperazic acid (Piz), a nonproteinogenic amino acid, are of significant interest for drug discovery. Peptidic compounds incorporating Piz as a building block include antibacterial, antiviral, immunomodulatory and anticancer drug leads, and all naturally-occurring Pi…
by | Sep 1, 2020 | Liao, Jie, Yang, Lan
— Technology Description
A team of engineers in Prof. Lan Yang’s laboratory have developed ultra-sensitive, broad bandwidth optical sensors that could detect sound in low-cost, discrete hearing devices. This technology utilizes whispering gallery mode (WGM) resonators as compact photonic vibra…
by | Jul 27, 2020 | Millman, Jeffrey, Song, Jiwon
— Technology Description
Researchers at Washington University in St. Louis have developed a 3D-printed device for the subcutaneous transplantation of stem cell-derived beta (SC-beta) cells for diabetes cell replacement therapy. Diabetes mellitus, a disease characterized by loss of blood glucose cont…
by | May 26, 2020 | Zhou, Dong
— Technology Description
Researchers at Washington University in St. Louis (WUSTL) have developed a new method and device for the preparation of flourine-18 (F-18) radiolabeled compounds as positron emission tomography (PET) tracers. PET is a widely used clinical and research imaging tool that will …
by | Apr 29, 2020 | Bach, Richard, Boyle, Walter
— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…