by | Jul 27, 2020 | Millman, Jeffrey, Song, Jiwon
— Technology Description
Researchers at Washington University in St. Louis have developed a 3D-printed device for the subcutaneous transplantation of stem cell-derived beta (SC-beta) cells for diabetes cell replacement therapy. Diabetes mellitus, a disease characterized by loss of blood glucose cont…
by | Jul 17, 2020 | Covey, Douglas, Mennerick, Steven
— Technology Description
Researchers at Washington University in St. Louis have developed new compounds that may be used to treat alcohol use disorder (AUD). AUD, a common condition that takes a high personal and public health toll, is characterized by severe problems with drinking- sufferers may co…
by | Jul 13, 2020 | Millman, Jeffrey, Velazco-Cruz, Leonardo
— Technology Description
Researchers at Washington University in St. Louis have developed an improved method to differentiate stem-cells into functionally mature, insulin-secreting beta cells (SC-beta cells). Pancreatic beta cells play an important role in controlling blood glucose levels as they se…
by | Jul 13, 2020 | Millman, Jeffrey, Velazco-Cruz, Leonardo
— Technology Description
Researchers at Washington University in St. Louis have developed an improved method to differentiate stem-cells into functionally mature, insulin-secreting beta cells (SC-beta cells). Pancreatic beta cells play an important role in controlling blood glucose levels as they se…
by | Jul 9, 2020 | Gong, Yong-feng, Hou, Jianghui
— Disease indication: metabolic disorders including insulin resistance and diabetic nephropathy
Drug format: chemically modified synthetic microRNA (miRNA)
Drug class: first-in-class for metabolic disease
Research stage and Preliminary data:
Target: miR-29 mimics can increase the gene expressio…