by | Jan 25, 2022 | Bowman, Gregory
— Technology Description
Researchers in Greg Bowman’s lab at Washington University have developed an improved method for rational drug and protein design called Boltzmann docking. This process better incorporates the dynamic structures of proteins to identify sites for binding that are not rev…
by | Sep 2, 2021 | Schreiber, Robert
— D42m1 is a methycholanthrene (MCA) induced sarcoma cell line generated in 129S6 strain RAG2 gene targeted mice. These cells are highly immunogenic and are rejected when transplanted into syngeneic naive wild type mice.
F244 is an MCA induced sarcoma cell line generated in wild type 129S6 mice. Thes…
by | Mar 17, 2021 | Djuranovic, Sergej
— Technology Description
Researchers in Prof. Sergej Djuranovic’s laboratory have discovered short DNA coding motifs that can increase or decrease expression of recombinant proteins by 3-4 orders of magnitude in a variety of organisms. Together, these universal tools can provide tightly contro…
by | Jan 20, 2021 | Barcellona, Marcos, Setton, Lori, Speer, Julie
— Background:
Severe low back pain and disability can result from intervertebral disc (IVD) degeneration caused by cell phenotype changes in the nucleus pulposus (NP) region. While autologous stem cells have be used to treat lower back pain, currently there are no tools to control differentiation of…
by | Jan 20, 2021 | Barcellona, Marcos, Setton, Lori, Speer, Julie
— Background:
Severe low back pain and disability can result from intervertebral disc (IVD) degeneration caused by cell phenotype changes in the nucleus pulposus (NP) region. While autologous stem cells have be used to treat lower back pain, currently there are no tools to control differentiation of…