by | Oct 22, 2019 | Crimmins, Dan, Gaut, Joseph, Ladenson, Jack, Laterza, Omar, Lockwood, Christina, Modur, Vijay
— Technology Description
A team of researchers at Washington University in St. Louis have developed patented antibodies designed to identify MIOX (myo-inositol oxygenase), a renal-specific biomarker that can be detected immediately following acute kidney injury (AKI). AKI can be caused by surgery, s…
by | Oct 22, 2019 | Ladenson, Jack, Landt, Yvonne, Laterza, Omar
— This is a monoclonal antibody specific for NT-Pro BNP and can be used singly in a competitive immunoassay to measure the amount of this analyte in blood samples for the purpose of diagnosis or monitoring of congestive heart failure. In addition, it could be used in a sandwich immunoassay with a mono…
by | Oct 22, 2019 | Ladenson, Jack
— Rabbit polyclonal antibodies were generated using two distinct 20-mer synthetic peptides corresponding to the unique C-terminal extension of HuCKI 3 using standard protocols. Final purification used the corresponding peptide immunogen affinity column. Possible uses: histological detection in tumors …
by | Oct 22, 2019 | Crimmins, Dan, Gaut, Joseph, Ladenson, Jack
— This novel immunohistochemical marker would be a valuable diagnostic aid to the practicing surgical pathologist who is confronted with this particular diagnostic challenge. Companies may license this antibody for clinical testing, or cases may be referred to Washington University for subspecialty c…