— Technology Description Researchers at Washington University in St. Louis have developed a software method that demonstrates high precision and specificity in detecting neural oscillations in time and frequency domains. Current methods to look at identifying peaks over 1/f noise within the power s…

— Technology Description Researchers at Washington University in St. Louis have developed models that can very accurately predict brain amyloidosis—Alzheimer’s disease status. Alzheimer’s disease (AD) is characterized by the accumulation of Amyloid-β (Aβ42) and hyperphos…

— Technology Description Researchers at Washington University in St. Louis have developed a set of novel bile acid biomarkers to screen, diagnose, and monitor the progression of Niemann-Pick type C (NPC) disease. Current testing for this disease takes an average of three months, is invasive (a skin…

— Technology Description Researchers at Washington University in St. Louis have developed a deep brain stimulation approach that can identify optimal stimulation parameters intraoperatively, which significantly reduces the amount of time spent on adapting stimulation parameters, thus reducing costs,…

— Technology Description Researchers at Washington University in St. Louis have developed an analysis stream to detect and measure spontaneous plasticity pulses in patients with brain injuries. In stark contrast to existing methodologies (resting-state functional MRI and resting state functional co…

— Value proposition: Fluorescent oxonol dyes that can be used to enhance bioimaging for the treatment of cancer. Technology Description Researchers at Washington University in St. Louis have developed a new class of fluorescent oxonol dyes that exhibit absorption and emission in the near infrared…

— Novel Composition Designed to Treat Nematode Infections Value proposition: Small molecule treatments designed to target the adult worm to treat nematode infections in animals. Technology Description Researchers at Washington University in St. Louis have developed novel small molecule treatment…

— T-020503 Endoscopic Mucosal Graft Stabilizer Used to Treat Urethroplasty Technology Description Researchers at Washington University in St. Louis have developed a sheath device designed to hold a segment of mucosal graft in the correct position to be applied over a stricture repair site. The she…

— Value Proposition: This invention uses antibodies to detect Cutibacterium acnes (C. acnes) infections. Technology Description Researchers at Washington University in St. Louis have developed antibodies that can identify Cutibacterium acnes (C. acnes), which opportunistically causes infection rang…

— Technology Description Researchers at Washington University in St. Louis have developed a new method for automatically differentiating accelerated heart rhythms caused by wide complex tachycardia (WCTs) into fast, or irregularly fast heart rhythms caused by ventricular tachycardia (VT) and suprave…

— T-018976 Software that Generates Radiology Reports using Deep Learning Technology Description Researchers at Washington University in St. Louis have developed a computational software method designed to assist radiologists with generating and correcting patient reports more effectively. Radiolo…

— T-020656 – Deep Tissue Diagnostics with Disposable Fiber-Optic Device Technology Description Researchers from the laboratory of Song Hu has developed a miniaturized fiber-optic device capable of minimally invasive measurements of deep-tissue biomechanical properties. The device can be rea…

— T-019577 – Lrp1 and the blood brain barrier Technology Description Researchers in Gaya Amarasinghe’s laboratory at Washington University have engineered new protein fragments (RVFV Gn) to target LRP1, which was recently identified as an essential entry factor for Rift Valley Fever Virus (RVF…

— T-018886 — Scalable Generation of Hematopoietic Progenitors from Human Pluripotent Stem Cells Technology Description In vitro generation of CD34+ hematopoietic progenitor cells (HPC) that faithfully recapitulate in vivo behavior is an area of ongoing research. A key characteristic of CD34+ …

— Radiotracers to detect early Parkinson’s disease Technology Description Researchers at Washington University in St. Louis, led by Dr. Zhude Tu, have developed two imaging agents for α-synuclein (α-syn) aggregation for use to diagnose early Parkinson’s disease, track dise…

— T-017429 Engineered Oncolytic Zika Virus Therapy for Glioblastoma Technology Description Researchers in the laboratories of Michael Diamond and Milan Chheda at Washington University have developed prospective treatments for glioblastoma (GBM) through the application of an engineered Zika virus (ZI…

— T-020357, T-020358, T-020744 Myocardial perfusion SPECT optimization Technology Description Researchers from the laboratory of Abhinav Jha at Washington University have devised methods to reliably improve and personalize myocardial perfusion SPECT imaging. The inventions include the following capa…

— T-020153 – Small Molecule Agonists of EphA Receptors to Ameliorate Diabetes Technology Description Blood glucose levels (left), post-treatment plasma glucagon (center) in WCDD301 treated NOD (non-obese diabetic) mice with moderate hyperglycemia. Blood glucose levels (right) in Streptozotocin-ind…

— T-020486 – Systems and Methods for Detection and Quantification of Axial Spondyloarthritis Technology Description Researchers at Washington University in St. Louis, led by Dr. Michael Paley, have developed an assay to diagnose axial spondyloarthritis (axSpA) in HLA-B*27-positive patients.…

— WGM microresonators are an immature technology with room for improvement Microresonators are optical devices that are an important component of microlasers used in optoelectronics, data communications, and sensing. Most microresonators are WGM type, which confine light to a very small volume for si…