Search returned 682 results
Improved Alzheimer’s Disease Detection Using Cell-Free RNA AnalysisCruchaga, Carlos ; Ibanez, Laura ; Cisterna Garcia, Alejandro
T-020079
— Published Date: 5/10/2025 Value Proposition: Method that uses plasma cfRNAs to differentiate Alzheimer’s disease from healthy controls. Technology Description Researchers at Washington University in St. Louis have developed a series of models using blood-based biomarkers to detect Alzheimer …
Blood-based Biomarkers for IL-23 Inhibitor Response in IBDDeepak, Parakkal ; Cao, Siyan
T-020960
— Published Date: 5/10/2025 Value Proposition: Diagnostic method that uses the patient’s PBMCs acquired before or immediately after the onset of IL-23 therapy to determine the presence of signatures indicative of long-term IL-23 response. Technology Description Researchers at Washington Univ…
GDF-15: A Diagnostic Biomarker for GlaucomaYoshino, Jun ; Apte, Rajendra
T-016002
— Published Date: 4/29/2025 Value Proposition: Novel biomarker that can be used as a diagnostic to identify glaucoma severity or progression in patients. Technology Description Researchers at Washington University in St. Louis have identified a novel biomarker, GDF15, for glaucoma that can detect …
WHICH-A.R.T: Method for Accurately Detecting Male InfertilityZhao, Peinan ; Santi Grau Perez, Celia ; Ferreira, Juan
T-020924
— Published date: 3/14/2025 WHICH-A.R.T: Method for Accurately Detecting Male Infertility Value Proposition: Fertility treatment designed to quickly and accurately detect the fertilization capacity of sperm. Technology Description Researchers at Washington University in St. Louis have developed…
Gene-Edited iNKT Cell Expressing Chimeric Antigen Receptor for the Treatment of CancerDiPersio, John ; Cooper, Matthew
T-018642
— Value Proposition: Engineered iNKT cells with potential as a “universal” source of immune effector cells to treat cancer. Technology Description Researchers at Washington University in St. Louis have developed a new composition of matter that uses gene-edited invariant natural kill…
AntiFake: Computer Method Designed to Prevent Unauthorized Speech SynthesisZhang, Ning ; Yu, Zhiyuan
T-020985
— Published Date: 2/14/2025 Value Proposition: Speech synthesizer that uses adversarial audio to prevent the creation of deepfakes. Technology Description Researchers at Washington University in St. Louis have developed a computer implemented method for generating audio content that introduces per…
Insect-Inspired Electronic-Nose Technology for Reliable, Robust and Real-World Chemical SensingSingamaneni, Srikanth ; Chakrabartty, Shantanu ; Raman, Baranidharan
T-020888
— Published Date: 2/14/2025 Value Proposition: Portable and deployable platform that uses an AI-enabled, nanoparticle-based e-nose to sense explosive volatile organic compounds. Technology Description Researchers at Washington University in St. Louis have developed a low-power electronic nose that…
Potent Inhibitors of Protein Synthesis for the Treatment of ToxoplasmosisUddin, Taher ; Sibley, Laurence David
T-020814
— Published date: 1/29/2025 Value Proposition: New chemical matter that blocks protein synthesis, eliminating infection and providing improved treatment for Toxoplasmosis. Technology Description Researchers at Washington University in St. Louis have identified a new chemical matter that can inh…
Electrode Device that Precisely Stimulates Sympathetic Nerves to Treat Asthma, Hypertension and Other ConditionsMoore, Amy ; Moran, Daniel ; Qin, Yidan (Ida) ; Ray, Wilson ; Zhang, Christopher ; Kamath, Ashwin ; MacEwan, Matthew ; Leuthardt, Eric ; Cloonan, Paige
T-017895
— Published date: 1/15/2025 Value Proposition: Implantable electrode device that can treat a plurality of medical diseases by stimulating or inhibiting select regions of sympathetic nervous system. Technology Description Researchers at Washington University in St. Louis have developed “SIMP…
“The Revolution Reservoir and Catheter Tip”: Non-clogging Shunt Catheter Tip for Improving SurgeryMoran, Daniel ; Shah, Manish ; Smyth, Matthew ; Stone, Samuel ; Wang, Lihong ; Winek, Michael ; Yang, Alexander ; Haydon, Devon ; Limbrick, David ; Marcus, Richard ; McLaughlin, Aaron ; Genin, Guy ; Leuthardt, Eric
T-011139
— Published date: 1/15/2025 Value Proposition: New device that will reduce or eliminate the need for repeated surgeries to clear blocked catheter tips in ventriculoperitoneal shunts. Technology Description Researchers at Washington University in St. Louis have developed a self-powered, rotating c…
Barbed Fixation Device for Improving Surgical SuturingFelder, John
T-018828
— Published date: 1/15/2025 Value Proposition: Barbed mesh wound closure device that eliminates the need for surgical suturing to close incisions of the skin and fascia. Technology Description Researchers at Washington University in St. Louis have developed a barbed rod device that can be used to …
Innovative Surgical Tool for Application of Bone Wax in Neurotologic and Skull Base SurgeryO'Connor, Zachary ; Shew, Matthew ; Smetak, Miriam ; Kim, Albert
T-020826
— Published date: 1/10/2025 Value Proposition: Novel instrument designed to improve application of bone wax during ear and lateral skull surgeries. Technology Description Researchers at Washington University in St. Louis have developed a novel surgical tool for bone wax application. Surgeries …
Osteogenic Screw System for Stimulating Bone GrowthMoran, Daniel ; Leuthardt, Eric
T-005419
— Published date: 1/9/2025 Value Proposition: Osteogenic device that provides a focal current through a bone construct to induce bone formation and fusion in patients. Technology Description Researchers at Washington University in St. Louis have developed an osteogenic screw system that can perfo…
Genetically Engineered Yeast Strain for the Treatment of Gastrointestinal Tumors with Immune Checkpoint Inhibitor TherapyKwak, Suryang ; Prusa, Jerome ; Wallace, Miranda ; Gorushi, Olivia ; Helmink, Beth ; Dantas, Gautam
T-020850
— Published date: 1/9/2025 Value Proposition: Genetically engineered yeast used to treat gastrointestinal tumors through the delivery of immune checkpoint inhibitor (ICI) proteins. Technology Description Researchers at Washington University in St. Louis have developed a genetically engineered …
Comprehensive Suite of Tools for Streamlining and Automating Testing of Radiotherapy MachinesGreen, Olga ; Hao, Yao ; Knutson, Nels ; Mutic, Sasa ; Rodriguez, Vivian ; Schmidt, Matthew ; Zhao, Tianyu ; Cai, Bin ; Sun, Baozhou
T-019435
— Value Proposition: Tool and software suite used to automate and improve testing quality of linear accelerators, thus increasing profit. Technology Description Researchers at Washington University in St. Louis have developed a comprehensive suite of hardware and software tools that enables ful…
Novel Combination Therapy that Improves Resistance to Tetracycline AntibioticsDantas, Gautam ; DeAngelo, Caitlin ; Williford, Emily ; Blake, Kevin ; Wencewicz, Timothy
T-020451
— Published Date: 1/4/2025 Value Proposition: New composition of matter that combines tetracycline class compounds with destructase inhibitors to overcome resistance to tetracycline antibiotics. Technology Description Researchers at Washington University in St. Louis have developed an enzymatic…
Novel Combination Therapy that Improves Resistance to Tetracycline AntibioticsPark, Jooyoung ; Vogel, Joseph ; Wencewicz, Timothy ; Forsberg, Kevin ; Gasparrini, Andrew ; Tolia, Niraj ; Dantas, Gautam
T-016593
— Published Date: 1/4/2025 Value Proposition: New composition of matter that combines tetracycline class compounds with destructase inhibitors to overcome resistance to tetracycline antibiotics. Technology Description Researchers at Washington University in St. Louis have developed an enzymatic…
Zbtb46: A Novel Target for Cancer TherapyKrchma, Karen ; Choi, Kyunghee ; Kabir, Ashraf Ul
T-020458
— Published Date: 12/31/2024 Value Proposition: Novel immune-gene therapy for treatment of cancer. Technology Description Solid neoplasms are difficult to treat using immune checkpoint inhibitors in part because of the immunosuppressive nature of the tumor microenvironment. Researchers at Washin…
Method for Pattern Generation in Temperature-Dependent Viscosity Fluids Utilizing Localized Convective CellsJain, Chhavi ; Solomatov, Viatcheslav
T-021221
— Technology Description Researchers at Washington University in St. Louis have developed a process for manufacturing molten materials, such as molten polymers, to create patterns. By controlling the temperature of a molten polymer and applying targeted heat pulses from lasers or other sources, th…
Retrograde-AAV Platform that Enables Multiplex Projection Tracing and Multi-Modal Profiling of Projection NeuronsYang, Lite ; Hahm, Hannah ; Liu, Fang ; Samineni, Vijay
T-020975
— Published Date: 12/21/24 Value proposition: Powerful, high throughput platform that allows for the multiplex tracing of projection neurons to obtain a snapshot of activity-dependent recruitment of distinct projection neurons and their molecular features. Technology Description Researchers at…