Search returned 669 results
Plasma-based cfRNA Biomarkers for Parkinson’s DiseaseBeric, Aleksandra ; Ibanez, Laura
T-021115
— Published Date: 5/13/2025 Value Proposition: Plasma cell-free transcripts that can be used as biomarkers to aid in the diagnosis and monitoring of Parkinsons Disease. Technology Description Researchers at Washington University in St. Louis have developed a panel of cell free RNA (cfRNA) biomark…
Targeting Neuronal Hyperexcitability to Treat Central and Peripheral Nervous System NF1 TumorsAnastasaki, Corina ; Gutmann, David
T-020010
— Published Date: 5/13/2025 Value Proposition: A novel approach to repurposing FDA-approved anti-epileptic drugs to treat brain and nerve tumors associated with neurofibromatosis type I, offering a faster, cost-effective pathway to address an urgent unmet medical need. Technology Description Neuro…
Engineered transient autoimmune (ETA) T cell therapy for CNS injuryKipnis, Jonathan
T-019788
— Published Date: 5/13/2025 Value Proposition: Promotion of recovery and reduction of neuronal damage following nerve injury, first T cell approach to neurological disorders. Technology Description Traumatic injuries to the spinal cord or the brain currently have limited treatment options, particu…
“Guardian” Brain Peptides as Autoimmune TherapeuticKim, Min Woo "Mitch" ; Kipnis, Jonathan
T-020431
— Published Date: 5/13/2025 Value proposition: New therapeutic modality that uses CNS self-peptides to treat autoimmune diseases, reducing neuroinflammation damage in an organ-specific manner. Technology Description Autoimmune diseases continue to debilitate countless individuals, increasing healt…
Manipulating T Cell Regulatory Genes to Improve CAR T Cell TherapySingh, Nathan
T-020330
— Published Date: 12/24/2024 Value proposition: An advanced CAR-T cell therapy engineered to reduce T cell exhaustion, enhancing durability and effectiveness in cancer treatment by overcoming one of the leading causes of long-term treatment failure. Technology Description Researchers at Washington…
Improved Alzheimer’s Disease Detection Using Cell-Free RNA AnalysisCisterna Garcia, Alejandro ; Cruchaga, Carlos ; Ibanez, Laura
T-020079
— Published Date: 5/10/2025 Value Proposition: Method that uses plasma cfRNAs to differentiate Alzheimer’s disease from healthy controls. Technology Description Researchers at Washington University in St. Louis have developed a series of models using blood-based biomarkers to detect Alzheimer …
Blood-based Biomarkers for IL-23 Inhibitor Response in IBDDeepak, Parakkal ; Cao, Siyan
T-020960
— Published Date: 5/10/2025 Value Proposition: Diagnostic method that uses the patient’s PBMCs acquired before or immediately after the onset of IL-23 therapy to determine the presence of signatures indicative of long-term IL-23 response. Technology Description Researchers at Washington Univ…
GDF-15: A Diagnostic Biomarker for GlaucomaYoshino, Jun ; Apte, Rajendra
T-016002
— Published Date: 4/29/2025 Value Proposition: Novel biomarker that can be used as a diagnostic to identify glaucoma severity or progression in patients. Technology Description Researchers at Washington University in St. Louis have identified a novel biomarker, GDF15, for glaucoma that can detect …
WHICH-A.R.T: Method for Accurately Detecting Male InfertilityFerreira, Juan ; Zhao, Peinan ; Santi Grau Perez, Celia
T-020924
— Published date: 3/14/2025 WHICH-A.R.T: Method for Accurately Detecting Male Infertility Value Proposition: Fertility treatment designed to quickly and accurately detect the fertilization capacity of sperm. Technology Description Researchers at Washington University in St. Louis have developed…
Gene-Edited iNKT Cell Expressing Chimeric Antigen Receptor for the Treatment of CancerDiPersio, John ; Cooper, Matthew
T-018642
— Value Proposition: Engineered iNKT cells with potential as a “universal” source of immune effector cells to treat cancer. Technology Description Researchers at Washington University in St. Louis have developed a new composition of matter that uses gene-edited invariant natural kill…
AntiFake: Computer Method Designed to Prevent Unauthorized Speech SynthesisYu, Zhiyuan ; Zhang, Ning
T-020985
— Published Date: 2/14/2025 Value Proposition: Speech synthesizer that uses adversarial audio to prevent the creation of deepfakes. Technology Description Researchers at Washington University in St. Louis have developed a computer implemented method for generating audio content that introduces per…
Insect-Inspired Electronic-Nose Technology for Reliable, Robust and Real-World Chemical SensingSingamaneni, Srikanth ; Chakrabartty, Shantanu ; Raman, Baranidharan
T-020888
— Published Date: 2/14/2025 Value Proposition: Portable and deployable platform that uses an AI-enabled, nanoparticle-based e-nose to sense explosive volatile organic compounds. Technology Description Researchers at Washington University in St. Louis have developed a low-power electronic nose that…
Potent Inhibitors of Protein Synthesis for the Treatment of ToxoplasmosisUddin, Taher ; Sibley, Laurence David
T-020814
— Published date: 1/29/2025 Value Proposition: New chemical matter that blocks protein synthesis, eliminating infection and providing improved treatment for Toxoplasmosis. Technology Description Researchers at Washington University in St. Louis have identified a new chemical matter that can inh…
Electrode Device that Precisely Stimulates Sympathetic Nerves to Treat Asthma, Hypertension and Other ConditionsMoore, Amy ; Moran, Daniel ; Qin, Yidan (Ida) ; Ray, Wilson ; Zhang, Christopher ; Kamath, Ashwin ; MacEwan, Matthew ; Cloonan, Paige ; Leuthardt, Eric
T-017895
— Published date: 1/15/2025 Value Proposition: Implantable electrode device that can treat a plurality of medical diseases by stimulating or inhibiting select regions of sympathetic nervous system. Technology Description Researchers at Washington University in St. Louis have developed “SIMP…
“The Revolution Reservoir and Catheter Tip”: Non-clogging Shunt Catheter Tip for Improving SurgeryLimbrick, David ; Marcus, Richard ; McLaughlin, Aaron ; Moran, Daniel ; Shah, Manish ; Smyth, Matthew ; Stone, Samuel ; Wang, Lihong ; Winek, Michael ; Yang, Alexander ; Haydon, Devon ; Genin, Guy ; Leuthardt, Eric
T-011139
— Published date: 1/15/2025 Value Proposition: New device that will reduce or eliminate the need for repeated surgeries to clear blocked catheter tips in ventriculoperitoneal shunts. Technology Description Researchers at Washington University in St. Louis have developed a self-powered, rotating c…
Barbed Fixation Device for Improving Surgical SuturingFelder, John
T-018828
— Published date: 1/15/2025 Value Proposition: Barbed mesh wound closure device that eliminates the need for surgical suturing to close incisions of the skin and fascia. Technology Description Researchers at Washington University in St. Louis have developed a barbed rod device that can be used to …
Innovative Surgical Tool for Application of Bone Wax in Neurotologic and Skull Base SurgeryShew, Matthew ; Kim, Albert ; O'Connor, Zachary ; Smetak, Miriam
T-020826
— Published date: 1/10/2025 Value Proposition: Novel instrument designed to improve application of bone wax during ear and lateral skull surgeries. Technology Description Researchers at Washington University in St. Louis have developed a novel surgical tool for bone wax application. Surgeries …
Osteogenic Screw System for Stimulating Bone GrowthMoran, Daniel ; Leuthardt, Eric
T-005419
— Published date: 1/9/2025 Value Proposition: Osteogenic device that provides a focal current through a bone construct to induce bone formation and fusion in patients. Technology Description Researchers at Washington University in St. Louis have developed an osteogenic screw system that can perfo…
Genetically Engineered Yeast Strain for the Treatment of Gastrointestinal Tumors with Immune Checkpoint Inhibitor TherapyKwak, Suryang ; Prusa, Jerome ; Wallace, Miranda ; Gorushi, Olivia ; Helmink, Beth ; Dantas, Gautam
T-020850
— Published date: 1/9/2025 Value Proposition: Genetically engineered yeast used to treat gastrointestinal tumors through the delivery of immune checkpoint inhibitor (ICI) proteins. Technology Description Researchers at Washington University in St. Louis have developed a genetically engineered …
Comprehensive Suite of Tools for Streamlining and Automating Testing of Radiotherapy MachinesHao, Yao ; Knutson, Nels ; Mutic, Sasa ; Rodriguez, Vivian ; Schmidt, Matthew ; Zhao, Tianyu ; Cai, Bin ; Green, Olga ; Sun, Baozhou
T-019435
— Value Proposition: Tool and software suite used to automate and improve testing quality of linear accelerators, thus increasing profit. Technology Description Researchers at Washington University in St. Louis have developed a comprehensive suite of hardware and software tools that enables ful…