[18F]WC-DZ-F is a derivative of [18F]FluorThanatrace and a radiotherapeutic agent. [18F]WC-DZ-F has suitable biodistribution profile, favourable logP and super metabolic stability in vivo. We have demonstrated that [18F]WC-DZ-F is capable of imaging PARP-1 expression in PC-3 prostate cancer xenograft tumor in small animal. [18F]WC-DZ-F can be a replacement of [18F]FluorThanatrace in the imaging of PARP-1 expression.
New PARP-1 Inhibitors for Imaging PARP-1 Expression in Vivo
Tech ID: T-018730