Summaries by Inventor Yoo, Andrew
MicroRNA-induced Direct Conversion of Human Adult Fibroblasts into Neurons
Abernathy, Daniel ; Yoo, Andrew
T-017136
Oh, Youngmi ; Yoo, Andrew
T-020121
Abernathy, Daniel ; Yoo, Andrew
T-017136
— Background: Studying late-onset neurodegenerative disorders using patient-specific neurons is one of the primary goals of precision medicine. The ability to generate human neurons that mimic the neurons of elderly individuals will provide an instrumental platform to model and study adult-onset neuro…
Antisense oligo to enhance neuronal survival in Huntington’s DiseaseOh, Youngmi ; Yoo, Andrew
T-020121
— Technology Description Researchers in Andrew Yoo’s laboratory at Washington University have developed an antisense oligonucleotide targeting a miRNA (miR-29b-3p) as a treatment for Huntington’s disease (HD). Inhibiting miR-29b-3p promotes neuronal survival by rescuing neurons from deg…