Summaries by Inventor Schaffer, Jean

Ceramide profiling for blood-based predictive screening for cardiovascular disease, heart failure and death
Ory, Daniel ; Peterson, Linda ; Schaffer, Jean

— Technology Description A team of researchers has developed a high throughput, FDA-compliant assay to predict coronary heart disease and mortality in the general population 6-10 years before the onset of disease. This fully validated two-dimensional liquid chromatography-tandem mass spectrometry (L…

Gadd7 haploinsufficient mutant CHO cell line
Listenberger, Laura ; Ory, Daniel ; Schaffer, Jean

— Gadd7 haploinsufficient mutant CHO cell line Inventors generated a mutant Chinese Hamster Ovary (CHO) cell line with disruption of one allele encoding Gadd7, a non-coding RNA. CHO cells were transduced with retrovirus at a low multiplicity of infection and mutants were isolated. Number of retrovira…

CHO Gadd7 knockdown clones and control
Brookheart, Rita ; Schaffer, Jean

— CHO Gadd7 knockdown cell lines Inventors generated two stable Chinese Hamster Ovary (CHO) cell lines with knockdown of gadd7 by transfecting cells with a custom siRNA plasmid targeting hamster gadd7 (KD1 and KD2) and a control CHO cell line by transfecting cells with a custom scrambled siRNA plasmi…


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