Summaries by Inventor Dolle, Roland
NRF2 inhibitors as cancer therapeutics
Bowman, Brittany ; Dolle, Roland "Ron" ; Lapak, Kyle ; Major, Michael "Ben" ; Medcalf, Matthew
T-019534
Asadi Jomnani, Farzad ; Dolle, Roland "Ron" ; Piston, David
T-020153
Bowman, Brittany ; Dolle, Roland "Ron" ; Lapak, Kyle ; Major, Michael "Ben" ; Medcalf, Matthew
T-019534
— Disease indication – Diseases related to oxidative stress, including cancer, autoimmune disease, and Toxoplasma infection Drug format – Small molecule Drug class – Best-in-class Research stage and preliminary data – The researchers have synthesized a series of pyrimethamin…
Small Molecule Agonists of EphA Receptors to Ameliorate DiabetesAsadi Jomnani, Farzad ; Dolle, Roland "Ron" ; Piston, David
T-020153
— T-020153 – Small Molecule Agonists of EphA Receptors to Ameliorate Diabetes Technology Description Blood glucose levels (left), post-treatment plasma glucagon (center) in WCDD301 treated NOD (non-obese diabetic) mice with moderate hyperglycemia. Blood glucose levels (right) in Streptozotocin-ind…
