Summaries by Inventor Chandra, Pallavi

Effective test for active tuberculosis infection
Chandra, Pallavi ; Coullon, Heloise ; Philips, Jennifer

— Technology Description Researchers in Jennifer Philips’ lab at Washington University in St. Louis have developed a more sensitive biomarker test for active tuberculosis infection. These biomarkers, found in the sputum and plasma, comprise of cholesterol metabolites that are cooperatively prod…

Treating Tuberculosis with Host-Directed Drug Targeting
Chandra, Pallavi ; Philips, Jennifer

— Background: Worldwide, there are over 10 million new cases of tuberculosis (TB) annually, resulting in 1.8 million deaths. This makes Mycobacterium tuberculosis (Mtb), the bacterium causing TB, the world’s leading infectious disease killer. Even for drug susceptible TB, the treatment courses a…


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