Data, Algorithms, Software Summaries
Cruchaga, Carlos
T-021415
— Published date: 9/18/2025 Value Proposition: Process that can be used to quantify the amount of DNA contamination in an RNA isolation tube. Technology Description Researchers at Washington University in St. Louis have developed a method to determine the amount of DNA contamination in an RNA extr…
AI-Empowered MR-guided Radiotherapy for the Treatment of CancerHollingsworth, Scott ; Kim, Taeho
T-021391
— Published date: 9/12/2025 Value Proposition: Innovative real-time prediction method that uses deep learning to track tumors. Technology Description Researchers at Washington University in St. Louis have developed a pioneering method that leverages prior 3D cine MRI and simulation CT scans to p…
FIVTools: Software Suite for Single-Cell and Micro-Raft ImagingBuchser, William ; Chandrasekaran, Vinay ; Gerbi, Emanuel ; Milbrandt, Josh ; Yenkin, Alex
T-021436
— Published date: 9/18/2025 Value Proposition: Software that can be used to distinguish between live and dead cells while allowing for the resorting of living cells. Technology Description Researchers at Washington University in St. Louis have developed a software suite that enables single-cell an…
Novel Method to Remove Electrical Stimulation Artifacts in Neural SignalsBrunner, Peter ; Demarest, Phillip ; Leuthardt, Eric ; Willie, Jon ; Xie, Tao
T-020905
— Published Date: 6/18/2025 Value Proposition: Software tool that uses a novel denoising method to remove electrical stimulation artifacts from electrophysiology data while preserving physiological signals. Technology Description Researchers at Washington University in St. Louis have developed …
AntiFake: Computer Method Designed to Prevent Unauthorized Speech SynthesisYu, Zhiyuan ; Zhang, Ning
T-020985
— Published Date: 2/14/2025 Value Proposition: Speech synthesizer that uses adversarial audio to prevent the creation of deepfakes. Technology Description Researchers at Washington University in St. Louis have developed a computer implemented method for generating audio content that introduces per…
Retrograde-AAV Platform that Enables Multiplex Projection Tracing and Multi-Modal Profiling of Projection NeuronsHahm, Hannah ; Liu, Fang ; Samineni, Vijay ; Yang, Lite
T-020975
— Published Date: 12/21/24 Value proposition: Powerful, high throughput platform that allows for the multiplex tracing of projection neurons to obtain a snapshot of activity-dependent recruitment of distinct projection neurons and their molecular features. Technology Description Researchers at…
Method To Remove Brain Stimulation Artifacts in Neural SignalsBrunner, Peter ; Leuthardt, Eric ; Willie, Jon ; Xie, Tao
T-020083
— Value proposition: Method and system for removing multiple types of brain stimulation artifacts in neural signals to improve neurological diagnoses and therapies. Technology Description Researchers at Washington University in St. Louis have developed a method to remove brain stimulation artifact…
Software used to Detect Neural Oscillations in the Time-Frequency SpaceBrunner, Peter ; Cho, Hohyun
T-020025
— Technology Description Researchers at Washington University in St. Louis have developed a software method that demonstrates high precision and specificity in detecting neural oscillations in time and frequency domains. Current methods to look at identifying peaks over 1/f noise within the power s…
Optimizing Patient Treatment through Electrical Stimulation for Targeted Deep Brain StimulationAdamek, Markus ; Brunner, Peter ; Leuthardt, Eric ; Willie, Jon
T-020028
— Technology Description Researchers at Washington University in St. Louis have developed a deep brain stimulation approach that can identify optimal stimulation parameters intraoperatively, which significantly reduces the amount of time spent on adapting stimulation parameters, thus reducing costs,…
System and method for non-invasive brain stimulation for cognitive enhancementBraver, Todd ; Ching, ShiNung ; Singh, Matthew ; Wheelock, Jacob
T-020194
— T-020194 System and method for non-invasive brain stimulation for cognitive enhancement Technology Description Researchers at Washington University in St. Louis have developed a system that enables near- real-time control of human brain activity using non-invasive transcranial electrical curr…
New Process for Diagnosing Abnormal Heart Rhythms AutomaticallyMay, Adam
T-019674
— Technology Description Researchers at Washington University in St. Louis have developed a new method for automatically differentiating accelerated heart rhythms caused by wide complex tachycardia (WCTs) into fast, or irregularly fast heart rhythms caused by ventricular tachycardia (VT) and suprave…
Software that Generates Radiology Reports using Deep LearningKansagra, Akash ; Rahbar, Kasra
T-018976
— T-018976 Software that Generates Radiology Reports using Deep Learning Technology Description Researchers at Washington University in St. Louis have developed a computational software method designed to assist radiologists with generating and correcting patient reports more effectively. Radiolo…
Myocardial perfusion SPECT optimizationJha, Abhinav Kumar ; Rahman, Md Ashequr ; Siegel, Barry ; Yu, Zitong
T-020357
— T-020357, T-020358, T-020744 Myocardial perfusion SPECT optimization Technology Description Researchers from the laboratory of Abhinav Jha at Washington University have devised methods to reliably improve and personalize myocardial perfusion SPECT imaging. The inventions include the following capa…
Software to predict low back pain from brain imagingHawasli, Ammar ; Jayasekera, Dinal ; Lamichhane, Bidhan ; Leuthardt, Eric ; Ray, Wilson
T-019322
— Technology Description: Researchers at Washington University, led by Eric Leuthardt, have developed software that can identify specific brain regions involved in chronic low back pain from neuroimaging data. This software, powered by machine learning, relies on differences in cortical thickness an…
Computer vision training system for robust artificial intelligence image classificationTong, Liang ; Vorobeychik, Yevgeniy ; Wu, Tong
T-019303
— Technology Description Researchers in Prof. Yevgeniy Vorobeychik’s laboratory have developed a new adversarial model and training methods to defend deep neural networks against physical attacks that corrupt image classifications. This system outperforms previous state-of-the-art techniques a…
Pressure recovery ratio (PRR) index for real-time assessment of heart failureChung, Charles ; Kovacs, Sandor ; Shmuylovich, Leonid ; Zhang, Weixiong
T-007562
— Technology Description Researchers in the Cardiovascular Biophysics Laboratory at Washington University developed a patented, real-time, automated index to reliably detect delayed relaxation during cardiac catheterization diagnostics. This technique, called pressure recovery ratio (PRR), serves as…
Machine learning methods for real-time MRI image processing: MRI-only radiation treatment planning and improving MR image resolutionGreen, Olga ; Mutic, Sasa ; Park, Chunjoo (Justin) ; Zhang, Hao
T-018522
— Technology Description A team of researchers at Washington University School of Medicine developed deep learning image processing techniques to improve MRI diagnostics and potentially enable faster, more precise MRI-guided radiation therapy without exposing patients to radiation from CT imaging. S…
Real-time air and water quality monitoring with AI-based data analysis and low cost sensorsBiswas, Pratim ; Li, Jiayu
T-018523
— Technology Description Prof. Pratim Biswas and colleagues have developed an artificial intelligence platform to provide accurate, low-cost analysis of air and water quality by integrating data gathered from particulate matter (PM) sensors and other sources. This technology could be used to make th…
Machine learning method for fast, reliable quality assurance of patient imaging in radiation therapy or computer-aided detectionAltman, Michael ; Green, Olga ; Kavanaugh, James ; Li, Hua ; Mutic, Sasa ; Wooten, Hasani
T-013577
— Technology Description A team of researchers at Washington University has created a machine learning method to quickly and reliably validate patient contours in digital medical images for radiation therapy and computer aided image analysis. Currently, automated contouring tools for delineating tu…
Blockchain-based algorithms for secure, collaborative risk assessment and decision makingJain, Raj ; Salman, Tara
T-018710
— Technology Description Researchers in Prof. Raj Jain’s laboratory have developed a new type of algorithm that extends the security of decentralized blockchains from consensus validation to efficient group decision making. This technology, called “probabilistic blockchains”, provi…
Self-powered, solid-state devices for remote sensing, timing and security of internet-of-things and other passive assetsChakrabartty, Shantanu ; Zhou, Liang
T-015908
— Technology Description Engineers in Prof. Shantanu Chakrabartty’s laboratory have developed a self-powered, CMOS-based, nano-scale “smart sensor” and timer system that uses quantum-tunneling for reliable, long-lasting memory or authentication. This technology is a floating gate …
Multiparametric Cardiac Strain Analysis of Myocardial ViabilityCupps, Brian ; Kar, Julia ; Pasque, Michael
T-014564
— Background: Assessing left ventricle (LV) cardiac contractile function is a good indicator of overall heart health and is used to determine which patients are good candidates for revascularization surgery. With over 3 million new coronary artery disease patients annually and over 1 million annual re…
Method to characterize gut microbiomeGordon, Jeffrey ; Raman, Arjun
T-018977
— Technology Description Researchers at Washington University in St. Louis have developed a method to stratify gut microbiota dysbiosis and monitor treatments to correct it. In order to efficiently treat microbiota imbalance, it would first be beneficial to understand the healthy organization and in…
EMMI- non-invasive imaging method for safe, accurate, robust monitoring of uterine contractionsCahill, Alison ; Cuculich, Phillip ; Schwartz, Alan ; Wang, Yong
T-015805
— Technology Description Researchers at Washington University in St. Louis have developed an electromyometrial imaging (EMMI) method to non-invasively monitor uterine contractions. During pregnancy, many women experience preterm contractions. Sometimes these contractions progress to pre-term labor a…
Accurate, efficient 2D strain mapping with robust detection of strain localizationBoyle, John ; Genin, Guy ; Pless, Robert ; Thomopoulos, Stavros
T-014090
— Summary DDE (Direct Deformation Estimation) and SIMPLE (Strain Interference with Measures of Probable Local Elevation) are two simple Digital Image Correlation algorithms that combine image analysis techniques with mechanical engineering principles to provide accurate, efficient, quantitative strai…
