by | Jul 18, 2024 | Kim, Brian
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Value proposition: Novel approach to treat chronic itch through the intrathecal or intranasal delivery of JAK inhibitors.
Technology Description
Researchers at Washington University in St. Louis have developed a new method for treating chronic idiopathic pruritus (CIP) in both patients and m…
by | Jan 5, 2021 | Feng, Jing, Hu, Hongzhen, Luo, Jialie, Yang, Pu
— Technology Description:
A team of researchers, led by Hongzhen Hu, at Washington University in St. Louis has developed a method of treating hair loss and alopecia by intradermal injection targeting TRPV4 activation. Using a small molecule TRPV4 agonist, a single intradermal injection is sufficient…
by | Oct 22, 2019 | Klechevsky, Eynav
— Background
Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…